60-56-0 MSDS - Methimazole
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Methimazole

Identification
Name Methimazole
CAS Registry Number 60-56-0
Synonyms TAPAZOLE;THIAMAZOLE;1,3-dihydro-1-methyl-2h-imidazole-2-thion;1,3-dihydro-1-methyl-2H-Imidazole-2-thione;1-methyl-2-mercapto-imidazol;1-methyl-imidazole-2-thio;1-Metylo 2 merkaptoimidazolem;1-metylo2merkaptoimidazolem
Molecular Structure Methimazole   60-56-0
Molecular Formula C4H6N2S
Molecular Weight 114.17
mp: 144-147 ℃(lit.)
Hazard Codes: Details
Risk Statements: 43-62-63
Safety Statements: 26-27-36-45-36/37
HS Code: 29332990
Supplier
Lightchem Inc
Supply Precious metal catalyst
OLED Materials etc.
www.lightchem.com
 
Wiki & MSDS
60-56-0.pdf
Thiamazole
Methimazole.svg
Thiamazole ball-and-stick.png
Clinical data
Trade names Tapazole, others
AHFS/Drugs.com Monograph
MedlinePlus a682464
Pregnancy
category
  • D (US)
Routes of
administration
by mouth
ATC code
  • H03BB02 (WHO)
Legal status
Legal status
  • AU: S4 (Prescription only)
  • US: ℞-only
Pharmacokinetic data
Bioavailability 93%
Protein binding None
Metabolism Liver
Biological half-life 5-6 hours
Excretion Kidney
Identifiers
Synonyms thiamazole (INN, BAN); methimazole (USAN); MMI
CAS Number
  • 60-56-0 YesY
PubChem CID
  • 1349907
IUPHAR/BPS
  • 6649
DrugBank
  • DB00763 YesY
ChemSpider
  • 1131173 YesY
UNII
  • 554Z48XN5E
KEGG
  • D00401 YesY
ChEBI
  • CHEBI:50673 YesY
ChEMBL
  • CHEMBL1515 YesY
ECHA InfoCard 100.000.439
Chemical and physical data
Formula C4H6N2S
Molar mass 114.17 g/mol
3D model (Jmol)
  • Interactive image
Melting point 146 °C (295 °F)
Solubility in water 275[1] mg/mL (20 °C)
  (verify)

Thiamazole (INN) or methimazole (USAN) is an antithyroid drug,[2] and part of the thioamide group. Like its counterpart propylthiouracil, a major side effect of treatment is agranulocytosis.


 







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